Scientific Program
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  • September 7 (THU)
  • September 8 (FRI)

Sep. 7 (Thu)

ASCO/KSMO Joint Symposium 1 (JS01)

Targeting rare genomic aberrations in precision oncology
Date & Time September 7 (Thu), 08:40-10:10 Venue Room A
Chairs
  • Everett E. Vokes (ASCO Past President, University of Chicago Medicine and Biological Sciences, USA)
  • Joong Bae Ahn (Chair, Board of Directors, KSMO, Yonsei Cancer Center, Republic of Korea)
Session Details
  1. 1. Targeting NTRK fusion-positive cancers
    Lori J. Wirth (Massachusetts General Hospital, USA)
  2. 2. Clinical implication of BRAF aberrations in solid tumor
    Miso Kim (Seoul National University Hospital, Republic of Korea)
  3. 3.Ancestry-specific differences in TMB
    Amin Nassar (Yale New Haven Hospital, USA)
  4. 4.RAS/RAF aberrations in refractory cancer: What is next?
    Hee Kyung Kim (Chungbuk National University Hospital, Republic of Korea)

Satellite Symposium 1 (SL01)

Date & Time September 7 (Thu), 08:40-09:20 Venue Room B
Chair
  • Young Joo Min (Ulsan University Hospital, Republic of Korea)
Session Details
  1. Pembrolizumab and chemotherapy combinations, the global SOC in the 1st line treatment for NSCLC, HNSCC, and esophageal cancer
    Ji-Hyun Park (Konkuk University Medical Center, Republic of Korea)

Satellite Symposium 2 (SL02)

New era of 1st-line treatment for GC/GEJ/EAC with Nivolumab
Date & Time September 7 (Thu), 09:30-10:10 Venue Room B
Chair
  • Min-hee Ryu (Asan Medical Center, Republic of Korea)
Session Details
  1. 1. Real-World Practice of PD-L1 Testing for Nivolumab Plus Chemotherapy in Gastroesophageal Adenocarcinoma
    Hye Seung Lee (Seoul National University Hospital, Republic of Korea)
  2. 2. New Era of 1L Treatment for HER2 negative GC / GEJC / EAC with Nivolumab
    Min Kyu Jung (Yonsei Cancer Center, Republic of Korea)

Scientific Symposium 1 (SS01)

T cells need our help to fight cancer, beyond PD-1/PD-L1 inhibitors
The use of T cells in cancer immunotherapy has become a potent weapon in the fight against cancer. While Immune checkpoint inhibitors like PD-1/PD-L1 inhibitors
have revolutionized cancer treatment, primary and acquired resistance continue to pose significant challenges. To overcome these limitations, Innovative forms of
immunotherapy, such as adoptive T cell transfer and T cell redirection therapy, are now being researched actively. During this session, we will discuss these exciting
advances in cancer immunotherapy and their potential to enhance treatment outcomes.
Date & Time September 7 (Thu), 08:40-10:10 Venue Room C
Chairs
  • Prasad S. Adusumilli (Memorial Sloan Kettering Cancer Center, USA)
  • Dae Ho Lee (Asan Medical Center, Republic of Korea)
Session Details
  1. 1. Tumor-infiltrating lymphocyte (TIL) therapy, around the corner?
    Omid Hamid (The Angeles Clinic and Research Institute, USA)
  2. 2. HPK1 is a novel target for immune checkpoint inhibition
    Eui-Cheol Shin (KAIST Graduate School of Medical Science and Engineering, Republic of Kroea)
  3. 3. Enhancing T-cell effector profile in adoptive T cell therapy
    Chungyong Han (National Cancer Center, Republic of Korea)
  4. 4. CAR T cells for solid tumors; Advances and barriers
    Prasad S. Adusumilli (Memorial Sloan Kettering Cancer Center, USA)

Scientific Symposium 2 (SS02)

The next step in the treatment of GU cancers
This genitourinary cancer session deals with "next step" therapy. It consists of the direction of clinical trials and future landscape of clinical practice of new drugs,
which are currently being introduced in the treatment of genitourinary cancer, and how to make the best treatment choice in areas where there is not yet full consensus.
First, we will learn and discuss BiTE and CAR T in prostate cancer and ADC in urothelial carcinoma, and next about choosing initial treatments in metastatic hormone-sensitive prostate cancer and advanced renal cell carcinoma.
Date & Time September 7 (Thu), 08:40-10:10 Venue Room D
Chairs
  • Jonathan Rosenberg (Memorial Sloan Kettering Cancer Center, USA)
  • Hyo Jin Lee (Chungnam National University Hospital, Republic of Korea)
Session Details
  1. 1. Bi-specific T cell engager and CAR T in castration resistant prostate cancer: Hope or hype?
    Mike Groaning (Amgen, USA)
  2. 2. Antibody-drug conjugate in urothelial carcinoma: Current status and future perspectives
    Jonathan Rosenberg (Memorial Sloan Kettering Cancer Center, USA)
  3. 3. Combination treatment in metastatic castration sensitive prostate cancer: What to combine and how to sequence?
    Woo Kyun Bae (Chonnam National University Medical School and Hwasun Hospital, Republic of Korea)
  4. 4. The First-Line Treatment of Metastatic Renal Cell Carcinoma
    Jae Lyun Lee (Asan Medical Center, Republic of Korea)

Plenary Lecture 1 (PL01)

Mechanisms of resistance to endocrine therapy in ER+ breast cancer
Professor Carlos L. Arteaga, M.D., is an internationally recognized expert in breast cancer in the areas of oncogenes and breast tumor initiation and progression, targeted
therapies and biomarkers of drug action and resistance, and investigator-initiated clinical trials in breast cancer. He is the Director of the Simmons Comprehensive
Cancer Center and Associate Dean of Oncology Programs at the University of Texas Southwestern Medical Center and served as the President of AACR. This plenary
lecture will be on resistance to endocrine therapy in breast cancer, with Dr. Arteaga giving his insights in tumor biology and novel therapeutics.
Date & Time September 7 (Thu), 10:40-11:20 Venue Room A
Chair
  • Seock-Ah Im (Seoul National University Hospital, Republic of Korea)
Session Details
  1. Mechanisms of resistance to endocrine therapy in ER+ breast cancer
    Carlos L. Arteaga (UT Southwestern Simmons Comprehensive Cancer Center, USA)

Luncheon Symposium 1 (LS01)

Date & Time September 7 (Thu), 11:30-12:10 Venue Room A
Chair
  • Sang-we Kim (Asan Medical Center, Republic of Korea)
Session Details
  1. Latest advances in small cell lung cancer treatment
    Hyun Ae Jung (Samsung Medical Center, Republic of Korea)

Luncheon Symposium 2 (LS02)

Date & Time September 7 (Thu), 11:30-12:10 Venue Room C
Chair
  • Kyung Hae Jung (Asan Medical Center, Republic of Korea)
Session Details
  1. Evolution and future of ribociclib in HR+HER2- mBC treatment
    Ji Yeon Kim (Samsung Medical Center, Republic of Korea)

Luncheon Symposium 3 (LS03)

Date & Time September 7 (Thu), 11:30-12:10 Venue Room E
Chair
  • Joo Hyuk Sohn (Yonsei University College of Medicine, Republic of Korea)
Session Details
  1. Change HER Destiny: Implementing ENHERTU in Practice and Practical Considerations
    Jae Ho JEONG (Asan Medical Center, Republic of Korea)

Scientific Symposium 3 (SS03)

Treatment for NSCLC: The earlier, the better?
There have been significant advances in adjuvant and neoadjuvant systemic chemotherapy for lung cancer, incorporating targeted agents and immunotherapy. These
clinical achievements are regarded as a significant opportunity to advance a cure for lung cancer. However, despite the progress, there are still limits in translating
clinical trial results into clinical practice. Further deliberation is needed to define more powerful predictive biomarkers before treatment or to develop subsequent
treatment strategies when expected responses are not achieved. In this session, we will discuss various clinical scenarios that arise when applying clinical research
results to real-world practice.
Date & Time September 7 (Thu), 12:30-14:00 Venue Room A
Chairs
  • Benjamin Besse (Gustave Roussy, France)
  • Sang-We Kim (Asan Medical Center, Republic of Korea)
Session Details
  1. 1. Neoadjuvant immunotherapy in NSCLC
    Mark Awad (Dana-Farber Cancer Institute, USA)
  2. 2. Adjuvant immunotherapy in NSCLC
    Benjamin Besse (Gustave Roussy, France)
  3. 3. Beyond treatment in recurred patients treated with upfront immunotherapy
    Hee Kyung Ahn (Gachon University Gil Medical Center, Republic of Korea)
  4. 4. Adjuvant EGFR TKI therapy, sooner is better than later, but not always!
    Dae Ho Lee (Asan Medical Center, Republic of Kroea)

Satellite Symposium 3 (SL03)

Date & Time September 7 (Thu), 12:30-13:10 Venue Room B
Chair
  • Keun Seok Lee (National Cancer Center, Republic of Korea)
Session Details
  1. Optimizing efficacy, safety and QOL balance of CDK 4/6 inhibitors in treating HR+/HER2- breast cancer patients
    Jieun LEE (The Catholic University of Korea Seoul St. Mary's Hospital, Republic of Korea)

Satellite Symposium 4 (SL04)

Date & Time September 7 (Thu), 13:20-14:00 Venue Room B
Chair
  • Jae Lyun Lee (Asan Medical Center, Republic of Korea)
Session Details
  1. The first ADC in la/mUC treatment, Enfortumab Vedotin landed in Korea
    In-Ho Kim (The Catholic University of Korea Seoul St. Mary's Hospital, Republic of Korea)

KSP/KSMO Joint Symposium (JS02)

Location matters: How spatial data is driving precision medicine
Date & Time September 7 (Thu), 12:30-14:00 Venue Room C
Chairs
  • Alexander Swarbrick (Garvan Institute of Medical Research, UNSW Sydney, Australia)
  • Yoon La CHOI (Samsung Medical Center, Republic of Korea)
Session Details
  1. 1. Spatial Transcriptomics in Oncology: Unveiling the Landscape of Tumor Heterogeneity
    Alexander Swarbrick (Garvan Institute of Medical Research, UNSW Sydney, Australia)
  2. 2. Current and future perspective of spatial transcriptome
    Jungmin Choi (Korea University College of Medicine, Republic of Korea)
  3. 3. The spatial context of tumor microenvironment
    Minsun Jung (Yonsei University College of Medicine, Republic of Korea)
  4. 4. Spatial tech to the clinic, how close are we? – A 10 years Singapore Odyssey to share
    Joe Yeong (Singapore General Hospital, Singapore)

KCSG/KSMO Joint Symposium (JS03)

The near future of precision medicine - One more step
Date & Time September 7 (Thu), 12:30-14:00 Venue Room D
Chairs
  • Dong-Wan Kim (Seoul National University Hospital, Republic of Korea)
  • Yeul Hong Kim (Yuhan Corporation, Republic of Korea)
Session Details
  1. 1. Spatial transcriptome analysis for cancer biology
    Woong-Yang Park (Samsung Medical Center, Republic of Korea)
  2. 2. The next horizon of precision oncology trials: Review of global research trends
    Yeon Hee Park (Samsung Medical Center, Republic of Korea)
  3. 3. Updates from the targeted agent and profiling utilization registry (TAPUR) study
    Richard L. Schilsky (The University of Chicago, USA)
  4. 4. Designing future clinical trials built on the basis of the KOSMOS II study
    Jee Hyun Kim (Seoul National University Bundang Hospital, Republic of Korea)

Scientific Symposium 4 (SS04)

Advance of perioperative chemotherapy in resectable or potentially resectable GI cancer
A deeper understanding of the molecular biology of cancer along with the introduction and application of new anticancer drugs have improved the efficacy of anticancer
therapy in metastatic digestive tract cancer. Recently, clinical trials on applying such effective chemotherapy even in cases where resection is possible have been actively
conducted, showing good results. In this session, we will discuss the peri-operative chemotherapy for resectable gastrointestinal cancer.
Date & Time September 7 (Thu), 14:10-15:40 Venue Room A
Chairs
  • Thierry CONROY (University of Lorraine, France)
  • Jong Gwang Kim (Kyungpook National University Chilgok Hospital, Republic of Korea)
Session Details
  1. 1. Application of perioperative chemotherapy for localized gastric cancer or gastroesophageal junction adenocarcinoma in Asian patients
    Sun Young Rha (Yonsei Cancer Center, Republic of Korea)
  2. 2. Present status and perspective of perioperative chemotherapy for patients with resectable pancreatic cancer
    Jin-Young Jang (Seoul National University Hospital, Republic of Korea)
  3. 3. Total neoadjuvant treatment in locally advanced rectal cancer
    Thierry Conroy (University of Lorraine, France)
  4. 4. Approach for resectable GI cancer with MSI-H
    Myriam Chalabi (Netherlands Cancer Institute, Netherlands)

Collaborative Symposium

Antibody-drug conjugates: Rise of new therapeutic strategies
Date & Time September 7 (Thu), 14:10-14:50 Venue Room B
Chair
  • Solange Peters (Lausanne University Hospital, Switzerland)
Session Details
  1. 1. Current and future perspectives on ADC strategies
    Solange Peters (Lausanne University Hospital, Switzerland)
  2. 2. Directing therapies to integrins in solid tumors
    Hyun Cheol Chung (Yonsei Cancer Center, Republic of Korea)

KOSRO/KSMO Joint Symposium (JS04)

Advances in non-operative, organ-preserving strategy
Date & Time September 7 (Thu), 14:10-15:40 Venue Room C
Chairs
  • Tomoya Yokota (Shizuoka Cancer Center, Japan)
  • Eui Kyu Chie (Seoul National University Hospital, Republic of Korea)
Session Details
  1. 1. Advances in non-operative, organ-preserving strategy
    William A. Hall (Medical College of Wisconsin, USA)
  2. 2. Multi-modality therapy to achieve intact-bladder survival
    Se Hoon Park (Samsung Medical Center, Republic of Korea)
  3. 3. Multidisciplinary less invasive approach for head and neck cancer
    Tomoya Yokota (Shizuoka Cancer Center, Japan)
  4. 4. Implication of immune cell (lymphocyte) dynamics during and after chemoradiotherapy in lung cancer patients undergoing maintenance immunotherapy
    Kyung Hwan Kim (Yonsei University College of Medicine, Republic of Korea)

Scientific Symposium 5 (SS05)

Advances in genomics technology and its clinical adaptation
The goal of this session is to showcase the latest advances in genomics technology and their clinical applications, fostering a deeper understanding of their potential in
shaping the future of personalized medicine. Our expert speakers will discuss the innovative EPIC-seq technique for inferring epigenetic expression from cell-free DNA
analysis, the integration of cell-free RNA in cancer studies, the use of whole-genome sequencing in clinical cancer diagnosis, and a data-centric approach that leverages
genomic and transcriptomic data to accelerate cancer drug discovery. Join us to explore the transformative potential of precision medicine in cancer.
Date & Time September 7 (Thu), 14:10-15:40 Venue Room D
Chairs
  • Maximilian Diehn (Stanford University, USA)
  • Duhee Bang (Yonsei University (Department of Chemistry), Republic of Korea)
Session Details
  1. 1. Circulating tumor DNA analysis for detection and molecular characterization of cancers
    Maximilian Diehn (Stanford University, USA)
  2. 2. Whole-genome sequencing for clinical diagnosis of cancer
    Young Seok Ju (Graduate School of Medical Science and Engineering, KAIST / Genome Insight Inc., Republic of Korea)
  3. 3. Single-cell RNA sequencing in analyzing molecular and cellular dynamics in lung cancer
    Hae-Ock Lee (The Catholic University of Korea, Republic of Korea)
  4. 4. Adopting a Data-Centric Approach to Fast Track Drug Target Identification - A Case Study
    Abhishek Jha (Elucidata Corporation, USA)

Oral Presentation 1 (OP01)

Date & Time September 7 (Thu), 14:40-15:40 Venue Room E
Chairs
  • Byoung-Yong Shim (The Catholic University of Korea St. Vincent's Hospital, Republic of Korea)
  • Tae-Yong Kim (Seoul National University Hospital, Republic of Korea)
Session Details
  1. 1. A Phase II Study of Tepotinib in patients with advanced solid cancers harboring MET exon 14 skipping mutations or amplification (KCSG AL19 -17)
    Eun Joo KANG (Korea University Guro Hospital, Republic of Korea)
  2. 2. A phase II study of autologous natural killer cells with hepatic arterial infusion chemotherapy in patients with locally advanced hepatocellular carcinoma
    Woo Kyun BAE (Chonnam National University Medical School and Hwasun Hospital, Republic of Korea)
  3. 3. A phase II study on the efficacy of regorafenib in treating patients with c-KIT-mutated metastatic malignant melanoma that progressed after previous treatment (KCSG-UN-14-13)
    Kyoo Hyun KIM (Yonsei University College of Medicine, Republic of Korea)
  4. 4. A phase I study of Nelmastobart (hSTC810), an anti-BTN1A1 antibody in advanced solid tumor patients
    Soohyeon LEE (Korea University Anam Hospital, Republic of Korea)
  1. 5. Combination immunotherapy targeting XBP1, CD138 and CS1 with cancer vaccine, checkpoint inhibitors, immune modulator, and epigenetic regulator to treat patients with myeloma or solid tumours: Clinical applications
    Jooeun BAE (Dana-Farber Cancer Institute, USA)

Plenary Lecture 2 (PL02)

Mechanism of action and inflammatory axis for air pollution induced non-small cell lung cancer
Professor Charles Swanton, FRCP BSc PhD, is a clinician scientist whose work is focused on understanding the challenges inherent in managing metastatic cancers
and their drug-resistant and incurable nature. He is the Chief Investigator of the TRACERx clinical study which deciphers lung cancer evolution, and his work has led
to insights in genomic diversity within cancers (intratumor heterogeneity) and molecular mechanisms driving cancer branched evolution.
Date & Time September 7 (Thu), 15:50-16:30 Venue Room A
Chair
  • Tae Won Kim (Asan Medical Center, Republic of Korea)
Session Details
  1. Mechanism of action and inflammatory axis for air pollution induced non-small cell lung cancer
    Charles Swanton (Francis Crick Institute, UK)

ESMO/KSMO Joint Symposium 1 (JS05)

Multiomics approach for precision medicine
Date & Time September 7 (Thu), 16:30-18:00 Venue Room A
Chairs
  • Andrés Cervantes (ESMO President, University of Valencia, Spain)
  • Kyung Hee Lee (KSMO President, Yeungnam University Medical Center, Republic of Korea)
Session Details
  1. 1. Biomarkers for Precision Oncology - Chances and Challenges
    Benedikt Westphalen (University of Munich, Germany)
  2. 2. Predictive factors for immunotherapy
    Rodrigo Dienstmann (Vall d'Hebron Institute of Oncology (VHIO), Spain)
  3. 3. Multiomics biomarker and immunotherapy: Yet to come
    Se-Hoon Lee (Samsung Medical Center, Republic of Korea)
  4. 4. Multiomics approach in EBV related solid cancer
    Jangho Cho (The Catholic University of Korea Incheon St. Mary's Hospital, Republic of Korea)

Satellite Symposium 5 (SL05)

Date & Time September 7 (Thu), 16:30-17:10 Venue Room B
Chair
  • Jong Gwang Kim (Kyungpook National University Chilgok Hospital, Republic of Korea)
Session Details
  1. Recent update in study for pattern, efficacy and safety of use of Bevacizumab or Cetuximab in patients with metastatic colorecatal cancer when added to FOLFIRI treatment
    Seung Hoon Beom (Yonsei Cancer Center, Republic of Korea)

Satellite Symposium 6 (SL06)

A new perspectives & future paradigm shift of treatment for advanced gastric cancer
Date & Time September 7 (Thu), 17:20-18:00 Venue Room B
Chair
  • Dae Young Zang (Hallym University Sacred Heart Hospital, Republic of Korea)
Session Details
  1. 1. How do we treat Advanced Gastric Cancer: biomarkers discovery and future systemic therapies?
    Jin-Soo Kim (Seoul National University BORAMAE Medical Center, Republic of Korea)
  2. 2. 2023 PRODIGY update: Role of Neoadjuvant with DOS regimen in locally advanced gastric cancer
    Hyung-Don Kim (Asan Medical Center, Republic of Korea)

Scientific Symposium 6 (SS06)

Artificial intelligence-empowered precision medicine in oncology: Cancer diagnosis, biomarker development, and drug discovery
Artificial intelligence (AI) technology has brought great changes in cancer diagnosis and treatment. A major example of using AI in the diagnostic field includes predicting
future cancer risk of individuals from normal mammography images before actual cancer development. By combining analysis of single cell sequencing technology and
pathology images, it is possible to analyze what genomic/transcriptomic features each cell has. In the therapeutic area, AI can predict the treatment response of novel
anti-cancer agents by analyzing the interaction between cancer cells and the microenvironment on a pathology slide. In addition, predicting and realizing the 3D structure
of proteins has led to great innovation in developing new drugs. In this session, experts in this field will share status updates on implementing AI in precision oncology
and share their perspectives.
Date & Time September 7 (Thu), 16:30-18:00
Venue Room C
Chairs
  • Jeanne Shen (Stanford University, USA)
  • Chaok Seok (Seoul National University, Republic of Korea)
Session Details
  1. 1. Machine Learning for Personalized Cancer Screening
    Adam Yala (UC Berkeley and UCSF, USA)
  2. 2. Development and clinical application of histopathology-based deep learning models for precision oncology
    Jeanne Shen (Stanford University, USA)
  3. 3. AI-powered analysis of spatial transcriptomics for drug development and biomarker discovery
    Kwon Joong Na (Seoul National University Hospital, Republic of Korea)
  4. 4. Searching chemical and protein spaces using deep neural networks for drug discovery
    Chaok Seok (Seoul National University, Republic of Korea)

Scientific Symposium 7 (SS07)

The blueprint for next-generation therapeutics
In this session, we introduce next-generation anticancer therapeutics that are currently being actively developed through phase 1/2 clinical trials. In the first presentation,
we will introduce PROTAC inhibitors, which are gaining attention as the next generation of protein degraders in the field of hormonal therapy. In the second presentation,
the presenter will review the current status of developing therapeutics for TP53 mutations, which are frequently found in all types of cancer but have lacked effective
treatments so far. In the third presentation, we will hear about the development status of ADCs (Antibody-Drug Conjugates) from LegoChem Biosciences, a Korean ADC
development company. Lastly, we are interested in hearing about the prospects of developing new HRD targeting agents, including PARP1 selective inhibitors.
Date & Time September 7 (Thu), 16:30-18:00
Venue Room D
Chairs
  • Ecaterina Elena Dumbrava (The University of Texas, MD Anderson Cancer Center, USA)
  • Joo Hyuk Sohn (Yonsei University College of Medicine, Republic of Korea)
Session Details
  1. 1. Development of Anti-Cancer PROTAC Agents
    Xin Gao (Massachusetts General Hospital, USA)
  2. 2. Targeting TP53 mutations using novel strategies
    Ecaterina Elena Dumbrava (The University of Texas, MD Anderson Cancer Center, USA)
  3. 3. New direction for ISAC development in cancer therapeutics
    Jeong-Hyun Ryou (Boostimmune, Inc., Republic of Korea)
  4. 4. Novel HRD targeting agents
    Elisabetta Leo (AstraZeneca, UK)